De México 664-979-2020     Toll Free 888-541-0202
 
 
De México
664-979-2020
Toll Free
888-541-0202

Clinical Development, Investigation & Research

CODET Vision Institute was founded in 1986 by Dr. Arturo Chayet in Tijuana, Mexico CODET is a 25,000 sq. ft., leading ophthalmology institute, consisting of the main sub-specialties:

  • Cornea, Refractive Surgery and Anterior Segment
  • Retina
  • Uveitis
  • Glaucoma
  • Oculoplastics
  • Pediatric Ophthalmology

Other key components of CODET are:

  • State-of-the-art operating rooms, laser eye surgery suites, and diagnostics lanes and kiosks equipped with the latest technology
  • State-of-the-art optometry practice and optical dispensary
  • Two-year fellowship programs in Cornea, Cataracts, Refractive Surgery, Glaucoma, and Retina
  • A dedicated clinical research department consisting of clinical investigators, IRB committee, regulatory support, strategic and product development consulting
  • Fundacion CODET: a foundation for low-income patients

Dr. Chayet has been a clinical trial investigator and consultant in the eye care industry since 1994. The main scope of his research and clinical work has been in the fields of refractive surgery and intraocular lenses. CODET Vision Institute is considered a top tier facility for clinical trials. Typically, Dr. Chayet is the first surgeon to test and perform new technologies for early stage vision care companies. Many of these companies' technologies have achieved FDA approval and are now used by several thousand ophthalmologists worldwide. Dr. Chayet's work involves all three phases of FDA clinical trials (Phase I, Phase II and Phase III). His center is certified by the Cofepris (Mexican Health Ministry) and several US FDA studies have been performed and are currently under way at CODET.

Additionally, Dr. Arturo Chayet has, himself, invented/developed the following technologies:

  • All-Laser-LASIK - 1995
  • Chayet LASIK Eye Drain - 1996
  • Bitoric LASIK - 1997

The 4 reasons to perform clinical trials with CODET:

1. Top Team

At CODET, we’ve developed over 20 years of experience performing clinical research for vision care startups and enterprises. Moreover, we take pride in working closely with our partner companies to help them design, develop, test, improve, and position their technology. Our team consists of the following members and capabilities, which will be discussed at greater length in the following sections:

  • Arturo Chayet, MD: Clinical Development & Investigation, R&D/Product Development, Strategy
  • Martha Federico: Study Coordination & Regulatory Affairs & GM of CODET’s Clinical Trials Department
  • Rosalinda Mota: Regulatory Strategic Partner and Consultant
  • Optometry Department: Led by Nora Robledo
  • Subspecialty Departments: Glaucoma & Retina 2-Year Fellowship
  • Gerardo Pozos, MBA: Operations & Strategy
  • Daniel Chayet, MBA: Business Development & Strategy

2. Top Technology

At CODET, we have the latest diagnostic equipment along with the most up-to-date surgical equipment.

3. Unique Location and Patient Dynamics

Unique Location

  • CODET is just 1 miles from San Diego, 20 miles from San Diego International Airport, and less than 100 miles from Orange County, CA, the ophthalmic device innovation hub. Members of clinical trial sponsor organizations that reside in the US or other countries can easily travel to CODET Vision Institute. Tijuana is a top 5 metropolitan area in Mexico in most categories. Its unique size, which is not too large or small, in addition to its proximity to the US, allows it go be a great location for clinical trials.

Patient Recruitment and Compliance

  • Tijuana’s unique size provides a wide enough pool of patients for fast and consistent recruitment, but a small enough geographic area and short enough commuting times to secure incredible patient compliance. CODET is well known for quick, reliable, and successful clinical trials where sponsors struggle very little to achieve their enrollment and follow up goals. CODET also has vast experience in first-in-human studies.

4. Unmatched Track Record

Startup clinical trial partners with successful investor outcomes:

  • 2013-2015: Oculeve (acquired by Allergan for $125M + milestone payments). First tear production device using intranasal lacrimal to treat dry eye CODET collaboration with design firm IDEO .
  • 2001-2008: IntraLase (acquired by AMO for $800M). First femtosecond laser for laser vision correction.
  • 1999-2002: Eyeonics (acquired by Bausch + Lomb for $800M) First accommodating intraocular lens for cataract surgery

Startup clinical trial partners that have raised significant capital and achieved important milestones to date:

  • 2002-present: Calhoun Vision / RxSight. First light adjustable lens for cataract surgery. Uses technology invented by Professor Robert Grubs for which he won the 2005 Nobel Prize in chemistry. Completed FDA Phase III trials.
  • 2002-2018: ReVision Optics. Corneal inlay for presbyopia correction. Secured FDA Phase III approval.
  • 2002-present: Ivantis. Minimally invasive implant to treat glaucoma. Initiated FDA Phase III trials.

Other Key Trials:

  • 1994-1996: Intelligent Surgical Laser (ISL): Picosecond-Excimer Laser Keratomileusis
  • 1994-2001: Keravision: Intracorneal Ring for the treatment of myopia and hyperopia
  • 1996-present: Nidek: Excimer laser. Microkeratome. OPD-scan. COS-2000.
  • 2003-2011: Abbot Medical Optics: Intraocular Lens Technologies
  • 2012-present: AbbVie: Human Anti-TNF Monoclonal antibody, Adalimumab
  • ​2013-2015: Alcon: Nepafenaco, Post-cataract diabetic patients
  • 2016-2017: XOMA: Eyeguard, Gevokizumab, treatment for Uveitis
  • 2016-2018: ClarVista Medical HARMONI Intraocular Lens Systems.
Established in 1986 · 1st IntraLASIK worldwide in 1995 · 1st Light Adjustable Lens worldwide in 2002
De México
664-979-2020
Toll Free
888-541-0202