{"id":798,"date":"2016-07-14T23:31:46","date_gmt":"2016-07-14T23:31:46","guid":{"rendered":"https:\/\/www.codetvision.com\/es\/?p=798"},"modified":"2021-03-18T00:02:27","modified_gmt":"2021-03-18T00:02:27","slug":"structural-changes-induced-by-a-corneal-shape-changing-inlay-deduced-from-optical-coherence-tomography-and-wavefront-measurements","status":"publish","type":"post","link":"https:\/\/www.codetvision.com\/es\/2016\/07\/14\/structural-changes-induced-by-a-corneal-shape-changing-inlay-deduced-from-optical-coherence-tomography-and-wavefront-measurements\/","title":{"rendered":"Structural Changes Induced by a Corneal Shape-Changing Inlay, Deduced From Optical Coherence Tomography and Wavefront Measurements"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Research and Development, ReVision Optics, Inc., Lake Forest, California, United States<br>CODET Vision, Tijuana, Mexico<br>Laser Ocular Hidalgo, Monterrey, Mexico<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-purpose\">PURPOSE:<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Changes to the anterior stroma and epithelium induced by a meniscus-shaped&nbsp;corneal inlay are presented. The hypothesis that local curvature is a driver of epithelial&nbsp;remodeling is tested.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-methods\">METHODS:<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Records of 30 subjects enrolled in a prospective clinical investigation of the inlay,&nbsp;implanted in emmetropic presbyopic subjects, were analyzed. The change to the anterior&nbsp;corneal surface was measured using wavefront techniques. The epithelial thinning profile was&nbsp;measured using Fourier domain optical coherence tomography. The stromal change was&nbsp;calculated from the two measurements.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-results\">RESULTS:<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The inlay\u2019s volume displaced the stroma anterior to the inlay, which was reflected&nbsp;in the change of Bowman\u2019s layer shape. The epithelium anterior to the inlay thinned by&nbsp;18.4 6 7.1 lm. Peripheral to the inlay\u2019s diameter (2 mm), circumferential epithelial&nbsp;thickening extended the change to the anterior corneal surface to approximately twice&nbsp;the inlay diameter. The central anterior corneal surface rose by 9.8 6 3.4 lm, creating a&nbsp;progressive add power profile. The epithelial thinning was linearly related to the&nbsp;curvature of the alteration to the anterior surface height, consistent with a theoretical&nbsp;model.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-conclusions\">CONCLUSIONS:<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">When a meniscus-shaped corneal inlay is placed beneath a corneal flap, the&nbsp;flap\u2019s stroma takes on predominately the inlay\u2019s shape. The epithelium remodels within a&nbsp;zone approximately twice the inlay diameter, with an anterior corneal height change&nbsp;providing improved near and intermediate vision. The relationship between the epithelial,&nbsp;stromal, and anterior corneal surface changes confirms the hypothesis that epithelial changes&nbsp;are greatest in regions of greater local surface curvature.<\/p>\n\n\n\n<div  class=\" b-buttons\" >\n\t\t\t<a  class=\"b-buttons__button a-btn a-btn--has-icon-after icon-arrow-right\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27409467\/\">\n\tLeer art\u00edculo<\/a>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Alan J. Lang, Keith Holliday, Arturo Chayet, Enrique Barrag\u00b4an-Garza, and Nikhita Kathuria.<\/p>\n","protected":false},"author":12,"featured_media":2804,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[142,57],"tags":[69],"class_list":["post-798","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vista-cansada-presbicia","category-publicaciones-cientificas","tag-publicacion-cientifica"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Structural Changes Induced by a Corneal Shape-Changing Inlay, Deduced From Optical Coherence Tomography and Wavefront Measurements - CODET Vision Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.codetvision.com\/es\/2016\/07\/14\/structural-changes-induced-by-a-corneal-shape-changing-inlay-deduced-from-optical-coherence-tomography-and-wavefront-measurements\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Structural Changes Induced by a Corneal Shape-Changing Inlay, Deduced From Optical Coherence Tomography and Wavefront Measurements\" \/>\n<meta property=\"og:description\" content=\"Alan J. 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